Clitoria ternatea pdf

B Treated in 48 hours. C Treated in 72 hours. The water extract had no effect on normal non cancer-origin cell growth. Figure 2 emphasizes the growth inhibitory effect of the methanol extract on MCF-7 cell lines Figure 2. This may be due contributed to the susceptibility of the cells to be to the presence of more active compounds into the aqueous extract of CT flowers. Furthermore, Rajan et water extract.

Shyam Kumar and Bhat due to the presence of flavonoids. Phenolic compounds, also added that petroleum ether extracted and including flavonoids are especially promising ethanolic extract of CT flowers had cytotoxic activity candidates for cancer prevention. Based on the growth inhibitory properties of the effectively against some types of cancer, particularly extracts observed, GC-MS analysis were obtained.

These compounds may from flowers of CT were mome inositol The GC-MS during in this study. However, further in vivo study is chromatogram of the methanol extracte Table 4 needed to confirm our findings and evaluating actual showed 15 peaks indicating the presence of three anti-proliferative properties in the CT flowers.

The components presented in the methanol extract from flowers of CT Conclusion were mome inositol Furthermore, Studies lines were observed in the water extract IC50 of In addition, it phenology, reproduction and potential nutraceutical, results from the proximate and mineral constituent pharmaceutical trait utilization.

Genetic Resources analysis at the plant has provided pertinent information and Crop Evolution 56 3 : Mukherjee, P. The Ayurvedic medicine Clitoria ternatea- From traditional use to scientific assessment. Journal Acknowledgements of Ethnopharmacology 3 : Oluyemi, E. Mineral contents of some technical guidance and support Ms. Lam Kit commonly consumed Nigerian foods. The authors are thankful Rabeta, M. Rajan, M. References In vitro cytotoxic activity of Clitoria Ternatea.

International 15th ed. Shyam K. In-vitro cytotoxic Cooper, G. The cancer book: a guide to activity studies of Clitoria ternatea Linn flower understanding the causes, prevention and treatment of extracts.

International Journal of Pharmaceutical cancer, p. Jones and Bartlett Learning. Sciences Review and Research 6 2 : Farooqui, M. Cancer T. The Journal of Nutrition treatment. BMC Public Health 11 1 : Finney, D. Probit analysis. Sodium nitrite-induced respiratory arrest The method described by Steru et al. Mice were divided in groups of five each. Sodium nitrite reduces the oxygen-car- 50 cm above the table top.

Duration of immobility was rying capacity of blood by converting hemoglobin to recorded for 6 min after discarding activity in the first 2 methemoglobin. This dose produces death due to respiratory min because animals try to escape during this period. Mice arrest in vehicle-treated mice Hock, Drugs increas- were considered immobile only when they hung passively ing cholinergic transmission delay or prevent the onset of and remain motionless.

Mice were treated with vehicle, CT respiratory arrest. CT Diazepam 1 The observations are given in Table 1. Catalepsy 3. In the second trial, when a new Statistical analysis familiar object as compared with the new object. The para- index. The observations are given in Table 2. Elevated plus maze Vehicle-treated mice spent Results dependently increased the time spent in the open arm 3.

Assessment of nootropic activity 3. Elevated plus maze On the first day, the mice entered the central platform TL On the second and ninth days, the TL was significantly reduced in all groups.

The duration of immobility was observed for 6 min after discarding activity during first 2 min. The head any significant effect. The observations are given in Table 3. Assessment of antidepressant activity box and The observations are given in Table 5. Assessment of anticonvulsant activity 3. Assessment of antistress activity 3. The animals that received vehicle died immedi- index. The effect produced by the lower doses of CT ately after seizures.

The observations are group that received CT, whereas only one animal died in given in Table 6. Lithium head twitches 3. MES-induced seizures In the vehicle-treated mice, the duration of tonic hin- Lithium induced Pirace- dlimb extension was The results of Vehicle CT the present investigation suggest that C.

The CT, though weak, 15 2. The extract reduced lithium- 45 3. The differences were not statistically significant. The nootropic drugs facilitate intellectual performance, learning and memory Giurgea, However, the neu- head twitches to We have reported decrease in brain contents of 3. It has been reported earlier that Clonidine induced hypothermia in vehicle-treated mice. The learning acquisition and memory consolidation Ogren, CT per se was without any effect on the rectal temper- The role of DA is, however, controversial.

Davis ature. Piracetam and CT did not significantly altered cloni- has shown that learning and memory can proceed dine-induced hypothermia. The observations are given in normally despite depletion of brain DA. Piracetam, an Table 7. However, in another 3. Sodium nitrite-induced respiratory arrest study, Bhattacharya et al. Brain DA The mice treated with sodium nitrite died after The increase in the IR and discrimina- treated mice. The CT met a major criterion for noo- tropic activity, namely, improvement of memory in absence 3.

Haloperidol-induced catalepsy of cognitive deficit Poschel, The EPM test min after haloperidol. The maximum catalepsy was is useful in screening effect on long-term memory, whereas noted 60 min after haloperidol. The intensity of catalepsy the object recognition test is useful to study the short-term was more prominent in the group that received CT before memory.

The improvement in IR by CT on the ninth day haloperidol. In CT-treated group, maximum catalepsy was indicated its weak effect on long-term memory. The CT potentiated haloper- CT exhibited a weak anxiolytic activity in both animal idol-induced catalepsy only unto 45 min.

Many CT alone was without any cataleptic activity. The observa- researchers have shown an inverted U-shaped dose — tions are given in Table 8. CT dose-dependently increased the time spent in 4. Discussion the open arm. In the Ayurvedic system of medicine, the roots, seeds and Several researchers have used this model for evaluation of leaves of C. In many anxiolytic agents Imaizumi et al. The observation that CT confusion and retards memory consolidation.

The amnesic increased time spent in the lit box is in congruence with effect of electroconvulsive shock, which is attenuated by these studies.

Many drugs that Clonidine, a presynaptic a-adrenoceptor agonist, induces increased the brain content of GABA have exhibited anti- hypothermia by reducing noradrenergic release Drew et al.

The MES is probably the best validated method for hypothermia, indicating that noradrenergic mechanism was assessment of antiepileptic drugs in the generalized tonic- not involved in the central effects of CT. The Sodium nitrite is known to convert hemoglobin into PTZ-induced seizures are similar to the symptoms observed methemoglobin, thereby reducing oxygen-carrying capacity in the absence seizures, and the drugs useful in the treatment and cholinergic transmission and ultimately leading to of absence seizures suppress PTZ-induced seizures McNa- death Hock, Piracetam and CT failed to decrease mara, CT significantly delayed the onset of convul- the effect of sodium nitrite.

This is the most important observation of the Existence of cognitive problem in depressive illness is present study because the modern medicine does not have well known Allain et al. This the most adverse effects on memory. A disturbed receptor these diseases.

Fluoxetine, a selective serotonin structures involved in the antipsychotic-induced catalepsy reuptake inhibitor, reduces total duration of immobility.

Duvoisin, In the present study, antidepressant response Barnes and Sharp, Total CT did not significantly increase haloperidol-induced cata- duration of immobility was decreased by CT. In addition, lepsy.

Brain DA level was found to decrease after admin- CT did not produce sedation and behavioral toxicity but istration of oil of C. This rather improved cognitive abilities. Thus, in conclusion, the extract was found the organism. Stress elicits various endocrinal and visceral to possess nootropic, anxiolytic, antistress and anticonvuls- changes including gastric mucosal integrity Ander, The present study is based on behavioral Stress increases brain serotonin level Bhattacharya and effects, and specific binding studies and measurement of Bhattacharya, and leaves a lasting imprint on cognit- neurotransmitter levels in freely moving animals are neces- ive behavior Jaiswal and Bhattacharya, Ray et al.

CT decreased ulcer index dose-dependently and showed antistress activity. References The increase in serotonergic transmission can interfere with learning acquisition and memory consolidation Ichi- Ander R. Breakdown in human adaptation to stress. Boston: Martinus Nijh- hara et al. The pharmacology of antidepres- Lithium-induced head twitches are due to increased forma- sants and senile dementia. Gerontologie; They are known to be rich sources of proteins, carbohydrates, lipids, vitamins, minerals, and other secondary metabolites.

To evaluate the presence of these compounds in marine macroalgae collected from Veraval coast of Gujarat, present studies was carried out. The methanol extract of six macroalgae species Ulva lactuca, Ulva faciata, Acantho Topical formulations may contribute to the reduction of oxidative stress in the skin.

Banana peel is a fruit waste with antioxidant activity that is not yet included in a topical formulation. The aim of this study was to evaluate the antioxidant and anti-aging activity of a cream formulation containing a lyophilized extract of banana peel.

The banana peel was extracted with ethanol, and a cream fo A new series of Schiff's base compounds were synthesized by condensation of 1- 4-amino-4 phenyl 3-phenyl triazeneol and substituted aldehyde and gave high yields of target compounds.

Antimicrobial activity of compounds has been tested against bacterial and fungal species, namely gram-positive bacteria as S. The antibacterial property of three Himalayan Oaks species Quercus floribunda, Q. It is an open access online and print International Journal published monthly. Website: www. Panchkula , HR. Why publish with us?